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Dr. Rhee and colleagues compared the identification of prediabetes, dysglycemia (diabetes or prediabetes), and diabetes by the recommended HbA1c-based screening with the conventional oral glucose tolerance test (OGTT).
Findings from a recent study, she said, suggest that the 50 gram glucose challenge test, a test used to screen for gestational diabetes in pregnancy, may represent a promising alternative to HbA1c as a screening test for diabetes or prediabetes (Phillips et al. Diabetologia. 2009;52:1798-1807) because it has been shown to be accurate and can be readily performed during office visits at any time of the day and without a prior fast.

 

Rimonabant (also known as SR141716; trade names Acomplia, Bethin, Monaslim, Remonabent, Riobant, Slimona, Rimoslim, Zimulti, and Riomont) is an anorectic antiobesity drug. It is an inverse agonist for the cannabinoid receptor CB1. Its main effect is reduction in appetite. Rimonabant was the first selective CB1 receptor blocker to be approved for use anywhere in the world.
Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. It is used to treat certain inflammatory diseases and (at higher doses) cancer, but has significant adverse effects. Because it suppresses the immune system, it leaves patients more susceptible to infections.

 

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